7 research outputs found

    Carbonic Anhydrases inhibitory effects of new benzenesulfonamides synthesized by using superacid chemistry

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    International audienceA series of benzofused sultams and fluorinated benzenesulfonamides were synthesized in superacid HF/SbF5 from simple N-allylic derivatives. Almost all of these original compounds showed micromolar inhibitory activities against carbonic anhydrases I and II. The fluorinated derivatives inhibit better the tumor-associated isoforms IX and XII, and one of the tested compounds showed inhibition in the nanomolar range

    π-1,1-Dimethyleneallylmetal and Homologous Complexes: Their Application in Organic Synthesis

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    Natural Occurrence, Syntheses, and Applications of Cyclopropyl-Group-Containing α-Amino Acids. 1. 1-Aminocyclopropanecarboxylic Acid and Other 2,3-Methanoamino Acids

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    Organocatalytic Asymmetric Epoxidation and Aziridination of Olefins and Their Synthetic Applications

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